• Disease Info
  • Key facts
  • Introduction
  • Epidemiology
  • Etiology
  • Extent of disease
• Pharmacology
  • Key facts
  • Chemistry and Pharmacy
  • Other BCG strains
  • Mode of action
  • Route of administration
  • Pharmacodynamics
• Efficacy
  • Key facts
  • Rationale for adjuvant therapy
  • Chemotherapeutic agents as adjuvant treatment
  • BCG as adjuvant treatment
  • Which tumors to treat
  • Optimal dose
  • Optimal schedule
  • Relationship between BCG side effects and efficacy
  • Management of treatment failures
• Safety & Tolerability
  • Key facts
  • Safety
  • Tolerability, Acceptability
• Treatment
  • Key facts
  • Indications
  • Contraindications
  • Dosing and administration
  • Interactions
  • Precautions & warnings
• Resources
  • Newsletters
  • Data Library
• Quick Overview
  • Abridged product information

| Glossary Site Map Disease Info Key facts Introduction Signs and symptoms Diagnosis Epidemiology Etiology Extent of disease Staging of the disease Grading of the disease Pharmacology Key facts Chemistry and Pharmacy Other BCG strains Mode of action Route of administration The intravesical route Pharmacodynamics Basic conditions for optimal antitumor results Efficacy Key facts Rationale for adjuvant therapy Chemotherapeutic agents as adjuvant treatment BCG as adjuvant treatment Which tumors to treat Low risk patients Intermediate risk patients High risk patients Optimal dose Clinical trials Conclusions Optimal schedule Maintenance schedule Rationale for maintenance treatment SWOG study EORTC study 30911 Optimal duration of maintenance treatment Side effects of maintenance treatment Conclusions Relationship between BCG side effects and efficacy Management of treatment failures Safety & Tolerability Key facts Safety Local side-effects Cystitis Hematuria Bladder Contracture Granulomatous prostatitis, epididymo-orchitis Upper urinary tract complications Systemic side-effects Flu-like symptoms, fever, malaise Systemic BCG infections Allergic reactions, rare complications Granulomas Serious adverse events Treatment recommendations for BCG related AEs Tolerability, Acceptability Treatment Key facts Indications Contraindications Dosing and administration Treatment dose Treatment Schedule Preparation of OncoTICE Warnings and precautions Safety in handling Reconstitution Preparation of the solution for instillation Administration of OncoTICE Patient instructions prior to OncoTICE instillation Instillation of OncoTICE Patient instructions after OncoTICE instillation Disposing and handling of OncoTICE pharmacy materials Healthcare worker safety OncoTICE accident instructions OncoTICE spills Interactions Precautions & warnings Resources Newsletters Data Library References Quick Overview Abridged product information

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